- Additional Authors
- Alternative Title
- QUERI
- Subject
- Note
- "Evidence-based synthesis program."
- "September 2013."
- Bibliography (note)
- Includes bibliographical references (pages 86-91).
- Funding (note)
- Source of Description (note)
- Description based on online resource; title from PDF cover (VA, viewed April 14, 2021).
- Call Number
- GPO Internet VA 1.107/3:AN 8/5
- OCLC
- 903315260
- Author
Filice, Gregory, author.
- Title
Antimicrobial stewardship programs in inpatient settings : a systematic review / prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center ; principal investigators, Gregory Filice, Dimitri Drekonja ; co-investigators, Timothy J. Wilt [and 3 others] ; research associates, Roderick Mac Donald [and two others].
- Publisher
Washington, DC : Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development, 2013.
- Description
1 online resource (v, 144 pages) : illustrations
- Type of Content
text
- Type of Medium
computer
- Type of Carrier
online resource
- Bibliography
Includes bibliographical references (pages 86-91).
- Summary
It is estimated that in 2009, more than 3 million kilograms of antimicrobials were administered to human patients in the United States. While the life-saving benefits of antimicrobials are indisputable, the consequences of use and misuse must also be considered. Major concerns related to the use of antimicrobials are increasing resistance, higher incidence of Clostridium difficile (C. difficile) infection (CDI) and increased healthcare costs (including costs related to adverse events associated with antimicrobial use). While much of the discussion focuses on overuse, there is also evidence of adverse outcomes associated with inadequate antimicrobial therapy. Antimicrobial stewardship programs (ASPs) are a focused effort by a health care system, a hospital, or a portion of a hospital (e.g., an intensive care unit) to optimize the use of antimicrobial agents. The goals of an ASP are to improve patient outcomes, reduce adverse consequences, reduce or prevent an increase in antimicrobial resistance, and deliver cost-effective therapy. The emphasis is on appropriate selection, dosing, route, and duration of antimicrobial therapy. The purpose of this review is to synthesize the evidence about the effectiveness of antimicrobial stewardship programs implemented in hospital settings. We focus on ASPs including one or more of the following components: prospective audit and feedback, formulary restriction, pre-authorization of prescriptions, guidelines for prescribing and/or modifying therapy, computerized decision support, or laboratory testing. The topic was nominated by Matthew Goetz, MD, Chief, Infectious Diseases, VA Greater Los Angeles Healthcare System, on behalf of the VA Antimicrobial Stewardship Task Force, and is intended to provide a summary of the evidence on inpatient antimicrobial stewardship programs to guide clinical practice and policy within the Veterans Healthcare System.
- Funding
VA-ESP 09-009
- Connect to:
- Added Author
Drekonja, Dimitri, author.
United States. Department of Veterans Affairs. Health Services Research and Development Service, issuing body.
Quality Enhancement Research Initiative (U.S.)
Minneapolis VA Health Care System (U.S.). VA Evidence Synthesis Program.
Evidence-based Synthesis Program (U.S.)
- Gpo Item No.
0985-A-12 (online)
- Sudoc No.
VA 1.107/3:AN 8/5
- Research Call Number
GPO Internet VA 1.107/3:AN 8/5